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Prostate Cancer Linked to Western Diet Related Links Top 10 Signs of Prostate Cancer Beer and Prostate Cancer -What Are the Facts? Enlarged Prostate -Causes and Top 10 Natural Remedies What Is Your Risk for Prostate Cancer? Prostate Cancer Links Page Peppers Kill Prostate Cancer Cells--10 Superfoods for Men Cancerous Tumors Have a Protective Shield Which Ibuprofen Attacks Can an Alkaline Diet Heal Cancer?- A Look at the Evidence Can Fast Food Make a Man Sterile? Ideal Weight for Men of Different Heights Blood Pressure-What It Means Foods That Reduce Blood Pressure Normal Penis Size Foods That Strengthen Erections Foods That Can Cause Erectile Dysfunction Penis Shaving Bumps-Home Remedies Best Way to Clean Your Penis National Institutes of Health -Prostate Health What do burgers and fries have to do with prostate cancer? Plenty, according to a new study by the Prostate Cancer Research Institute. Their research shows that men who eat fatty Western diets face a higher risk of developing prostate cancer. How much higher? Here's a comparison. The county of Qidong in China has the lowest recorded incidence rate, 0.5 per 100,000 men. By comparison, Sweden has a rate of 55.3 per 100,000 men and the U.S. has a rate of 102.1 per 100,000. Put another way, if you are a man in the United States, you have a 200 times greater risk of developing prostate cancer than a man in this province of China. And you have almost double the risk of developing cancer than a man in Sweden. Obesity promotes the development of cancer. As proof, the study observes that Asian men who live in China and Japan suffer extremely low rates of prostate cancer. But when these men move to the United States or other Western countries, their diets change, and they "increase their risk of cancer within a single generation". Article Continues Below. Several research studies have confirmed the link between fatty diets, obesity and prostate cancer. Fat emits hormones which have been implicated in the development of many forms of cancer, including prostate cancer, pancreatic cancer, ovarian cancer, lung cance, breast cancer, uterine cancer, kidney cancer and gallbladder cancer). All of these are epithelial cell cancers. And interactions between epithelial and other components (stromal components) inside cell tissues --as well as hormones that the organs through the circulation of your blood -- stimulate the growth of cancerous tumors. Hormones may increase the growth of cancerous tumors in 4 different ways. 1. Obesity Boosts Levels of Natural Steroids in Your Body. When you are obese, the fat increases teh production of steroids that stimulate growth of cells throughout your body. These steroid hormones can bind to nuclear receptors in tumor cells. Estrogen is one such hormone. Fat tissues produce excess amounts of estrogen. It's one of the reasons that cancers occur in fatty tissues such as breats. It's also one of the reasons that excess fat on a man's body increases hi chances of developing prostate cancer. 2. Obesity Increases Free Floating Hormones. Obesity increases the amount of free-floatng estrgen and testosterone in your blood stream. These free floating hormones can create havoc by binding to tumors. 3. Obesity Triggers DNA Damage. Third, steroid hormone action can trigger increased oxidant-stress-promoting cell proliferation and DNA damage. Androgens have been demonstrated to increase oxidant stress in prostate cancer cells, and oxidant defense mechanisms have been shown to be impaired early in the cancer process. 4. Obesity Encourages Paracrine Factors. Obesity can increase the production of paracrine factors and hormones which stimulate the production of steroid hormones in cancer tissue through interactions between stromal and epithelial compartments in tissues. Many of these paracrine factors are cytokines produced by both fat cells and white blood cells. Related Links Peppers Kill Prostate Cancer Cells--10 Superfoods for Men Signs of Testicular Cancer Soy Food Reduces Sperm Count Prostate Cancer -Top 10 Signs That You Have Prostate Cancer Want Access to More Articles Like This One?-Register -It's Free and Easy. Our "Members Only" Area Gets First Look at Articles, Reviews of and links to free video sites. References 1. Heber D, Blackburn GL, Go VLW (eds). Nutritional Oncology. Academic Press, San Diego CA, 1999. 2. Jaax S, Scott LW, Wolf JE, Thornby JI, and Black HS. General guidelines for a low fat diet effective in the management of nonmelanoma skin cancer. Nutr. Cancer 1997; 27:150-156. 3. Armstrong B, Doll R. Environmental factors and cancer incidence and mortality in different countries, with special reference to dietary practices. Int. J. Cancer 1975; 15: 617-631. 4. Shimizu H, et al. Cancers of the prostate and breast among Japanese and white immigrants to Los Angeles County. Br. J. Cancer 1991; 63: 963-966. 5. Garfinkel L. Overweight and Cancer. Ann of Int Med. 1985; 103:1034-36. 6. Newman SC, Miller AB, and Howe GR A study of the effect of weight and dietary fat on breast cancer survival time. Am J Epidemiol 1986; 123: 767. 7. Heber D. The role of nutrition in cancer prevention and control. Oncology 1992;6: 9-14. 8. Nimrod A, Ryan KH: Aromatization of androgens by human abdominal and breast fat tissue. J Clin Endo Metab 1975;40:367. 9. Kissebah AH, Evans DJ, Peiris A, et al. Endocrine characteristics in regional obesities: Role of sex steroids. In Vague J, Bjorntorp P, Guy-Grand B et al (eds). : Metabolic Complications of Human Obesities. Amsterdam, Excerpta Medica,1985, p. 115. Sources: Prostate Cancer Research Institute Source: Prostate Cancer Research Institute The Linkage Between Obesity and Prostate Cancer David Heber, MD, PhD, FACP, FACN Professor of Medicine and Director, UCLA Center for Human Nutrition Reprinted from PCRI Insights May 2004 vol. 7, no. 2 |
| Men Who Eat Western Fatty Diets Have Higher Risk of Prostate Cancer |
| Quick Fact: The county of Qidong in China has the lowest recorded prostate cancer incidence rate, 0.5 per 100,000 men. By comparison, Sweden has a rate of 55.3 per 100,000 men and the U.S. has a rate of 102.1 per 100,000 |
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