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Does Creatine Cause Asthma?-- A Comprehensive Review Related Links Top 10 Creatine Side Effects-A Comprehensive Review Whey versus Creatine -Which Is Better? BCAA's-Do They Improve Your Strength? Bench Press Average Celebrity Workouts Tiger Woods Workout Yoga to Strengthen Erectile Performance Yoga At Your Desk to Release Tension Foods That Help You Maintain Your Erection Normal Penis Size Get Lean Diet for Men October 4, 2011 By L. Carr, Associate Editor and Featured Columnist If you’ve ever sweated it out in a gym full of fitness fanatics and bodybuilders, chances are you’ve been pounding the treadmill or lifting weights next to someone who takes creatine. But is creatine completely safe? Certain reports have linked creatine with an increased risk of asthma. According to the American College of Sports Medicine, creatine is a piping-hot product for fitness - around $400 million-worth of creatine flies off the shelves every year in the United States. But if you suffer from asthma, should you take the popular supplement creatine? Will creatine make breathing problems more likely for you? What is Creatine? Creatine is used to enhance athletic performance and increase muscle mass. The supplement, discovered in 1832, is a nitrogenous organic acid that we have naturally in our bodies. If you eat enough protein from meat and fish, you will make enough creatine for good health. Creatine helps transport energy to our muscles, hence its use as a supplement in sport and fitness today. Many studies have reported success for people using creatine as a sport enhancer, particularly for activities that require short bursts of energy. The University of Maryland Medical Center, recommends exercisers take a start (or load) level of 5g of creatine, four times a day, for one week. Following this, the creatine maintenance dose could be between 2g and 5g a day. Taking creatine with simple carbohydrates can enhance its effect. What is the Link between Athletes and Asthma? Asthma is a serious chronic condition causing inflammation inside the airways and narrowing of the airways. Asthma affects up to 7.9 percent of Americans, according to the United States Environmental Protection Agency in 2009. Prevalence of asthma and allergies in top athletes is high. According to a 2010 study from the Clinical Center of the Ludwig Maximilian University, Germany there is an increased risk of asthma diagnosis and treatment for athletes involved in endurance sports compared to the general population. As creatine is a popular supplement for athletes, it has been suggested that there is a link between creatine and asthma risk. What is the Link between Creatine and Asthma? According to the National Heart Lung and Blood Institute, the exact cause of asthma is not known. Experts think genetic and environmental factors, most probably early in life, link together to cause asthma. These include an inherited tendency to develop allergies, parents with asthma and exposure to respiratory infections in infancy as well as contact with allergens or exposure to viral infections in early childhood. While there may be many causes of asthma, there have been reports linking creatine to an increased risk of developing the condition. Creatine may increase the chances of developing asthma in people already susceptible to the disease. The main evidence behind this hypothesis is research carried out in Brazil. A 2007 study from the School of Medicine at the University of São Paulo, Brazil, reported that creatine can make the symptoms of asthma worse by generating inflammation in the airways. In the study, creatine worsened the lung allergic response in mice modeled to suffer from chronic allergic lung inflammation. A follow-up 2010 study from the University of Sao Paulo, Brazil found that creatine activates airway epithelium in asthma – an important inflammatory factor in the development of asthma. Exercise Can Limit The Negative Effects of Creatine But it seems that the link between creatine, exercise and asthma is not clear. According to experts, when you take part in aerobic exercise you actually decrease or eliminate creatine’s purported negative effect on the airways. A 2009 study from the University of Freiburg, Germany reported that combining creatine with endurance training reduced the negative effect of creatine on the lungs. Exercise cuts the concentration of inflammatory cells in the lungs, and reduces the thickness of the muscles in the airways. If you’re taking creatine to increase your athletic performance you’re likely to be taking part in aerobic activity – so in theory creatine won’t increase your risk of asthma. Does Creatine Cause Asthma? The good news is -- probably not. Reports into the general safety of creatine have turned up little to worry about. A 1998 study from the University of Washington School of Medicine, Seattle showed short-term use (fewer than 28 days) of creatine at recommended dose did not cause significant adverse effects. No side effects were found when creatine was used at a high dose (15g to 30g a day) for 10 months to five years, according to a 2000 report into football players given at the American College of Sports Medicine 2000 Annual Scientific Meeting. Evidence that creatine significantly affects the performance of your airways is inconclusive. It may be that the increased prevalence of asthma in endurance athletes is not linked to any supplementation but could be due to better medical surveillance and treatment of athletes who rely on their body to help them perform. Put simply, many athletes suffer from asthma and they also take creatine; but whether creatine or exercise is responsible for asthma attacks is unclear. 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